Bedaquiline drug was developed to treat which of the following diseases?
The correct answer is MDR-TB.
Key Points
- Bedaquiline is used specifically to treat MDR-TB patients.
- MDR-TB stands for Multidrug-resistant tuberculosis. In this specific type of TB, the patient is resistant to the common drugs that are used to treat TB.
- The most common medications used to treat tuberculosis are Isoniazid, Rifampin (Rifadin, Rimactane), Ethambutol (Myambutol), Pyrazinamide.
- Bedaquiline was discovered by a team led by Koen Andries at Janssen Pharmaceutica.
Important Points
| Acute Myeloid Leukemia | - It is a cancer of the blood and bone marrow.
- With AML, the bone marrow makes abnormal blood cells including:
- Myeloblasts—a stem cell that evolves into specific types of white blood cells that help the body fight infection.
- Red blood cells (RBCs)—carry oxygen.
- Platelets—a blood component involved in clotting blood.
- Treatment of AML usually involves 2 phases:
- Remission induction therapy—to kill leukaemia cells.
- Maintenance therapy—to kill any remaining leukaemia cells that could grow and cause a relapse.
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| Cholera | - Cholera is a bacterial infection.
- They grow and release a toxin in the small bowel. You get it when you drink water or eat food that had contact with infected human stool.
- Diarrhoea causes rapid fluid loss.
- Cholera is common in places that don’t have proper sewage treatment.
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| Osteoarthritis | - Osteoarthritis (OA) is the wearing down of the cartilage between bones.
- Cartilage is smooth tissue that cushions bones and helps them move smoothly over each other.
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